In mice, anxiety is linked to immune system

Thursday, October 30, 2008 - 10:09 in Biology & Nature

In the first study ever to genetically link the immune system to normal behavior, scientists at Rockefeller and Columbia universities show that mast cells, known as the pharmacologic bombshells of the immune system, directly influence how mice respond to stressful situations. The work, to appear this week in the Proceedings of the National Academy of Sciences and to be highlighted in Science, chips away at the increasingly stale idea that the two most complex systems in the body have entirely separate modes of operation.

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