“Inactive” ingredients may not be, study finds

Wednesday, March 13, 2019 - 13:30 in Health & Medicine

Most pills and capsules, whether over-the-counter or prescription, include components other than the actual drug. These compounds, known as “inactive ingredients,” help to stabilize the drug or aid in its absorption, and they can make up more than half of a pill’s mass. While these components are usually considered benign, a new study from MIT and Brigham and Women’s Hospital has found that nearly all pills and capsules contain some ingredients that can cause allergic reactions or irritations in certain patients. In most cases, doctors have no idea which of these ingredients will be included in the pills they prescribe to their patients, because there are so many different formulations available for any given medication. “For most patients, it doesn’t matter if there’s a little bit of lactose, a little bit of fructose, or some starch in there. However, there is a subpopulation of patients, currently of unknown size, that will be...

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