Researchers Identify New Gene that Stimulates the Release of Calcium in Cells

Wednesday, April 22, 2009 - 12:42 in Biology & Nature

International research collaborators have identified a new family of proteins, TPC2 (two-pore channels), that facilitates calcium signaling from specialized subcellular organelles. The study, to be published April 22 in Nature, is the first to isolate TPC2 as a channel that binds to NAADP, a second-signaling messenger, resulting in the release of calcium from intracellular stores.

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