Chemotherapy resistance:Checkpoint protein provides armor against cancer drugs

Tuesday, September 1, 2009 - 13:35 in Health & Medicine

Cell cycle checkpoints act like molecular tripwires for damaged cells, forcing them to pause and take stock. Leave the tripwire in place for too long, though, and cancer cells will press on regardless, making them resistant to the lethal effects of certain types of chemotherapy, according to researchers at the Salk Institute for Biological Studies.

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