Nuclear Pore Complexes Harbor New Class of Gene Regulators, Offer Clues to Gene Expression and Cancer

Nuclear pore complexes are best known as the communication channels that regulate the passage of all molecules to and from a cell's nucleus. Researchers at the Salk Institute for Biological Studies, however, have shown that some of the pores' constituent proteins, called nucleoporins, pull double duty as transcription factors regulating the activity of genes active during early development.

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