Compounds Show Promise in Blocking STAT3 Signaling As Treatment for Osteosarcoma

A study appearing in the journal Investigational New Drugs and conducted by researchers at Nationwide Children's Hospital, discovered that two new small molecule inhibitors are showing promise in blocking STAT3, a protein linked to the most common malignant bone tumor, osteosarcoma. These small molecule inhibitors - one derived from a portion of the turmeric spice - may serve as a new, non-toxic treatment for these deadly tumors.

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