Screening for Matrix Effect in Leukemia Subtypes Could Sharpen Chemotherapy Targeting
Friday, December 5, 2014 - 11:00
in Physics & Chemistry
Jae-Won Shin and David Mooney of Harvard University's Wyss Institute for Biologically Inspired Engineering in Cambridge, MA, describe building a three-dimensional (3D) hydrogel system with tunable stiffness to see how relative stiffness of the surrounding ECM affected the resistance of human myeloid leukemias to chemotherapeutic drugs.