NYU Research: Shedding Light on Genetic Switches

The study, "Brachyury, Foxa2 and the cis-Regulatory Origins of the Notochord," published December 18, 2015, in PLOS Genetics, analyzes the regions of DNA that switch on gene expression in the notochord, called notochord cis-regulatory modules (CRMs, also known as enhancers). The paper presents a systematic analysis of CRMs that share the distinctive property of turning on gene expression in the notochord.

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