3D reconstruction of a vital interaction
Tuesday, February 3, 2015 - 08:30
in Biology & Nature
Researchers at IBS (CEA/CNRS/Joseph Fourier University) have succeeded for the first time in observing, on an atomic scale, the path taken and the successive changes in form undergone by a disordered vital protein, from its free state to the moment when it binds to another viral protein. The dynamics and mechanisms of this protein interaction, which is involved in the multiplication of the Sendai virus, yield information that could lead to the development of novel anti-viral drugs. This work was published in the Journal of the American Chemical Society on January 20, 2015.