The Largest Molecule Ever Made Could Be Used to Deliver Drugs

Tuesday, January 11, 2011 - 10:21 in Physics & Chemistry

Mega Macromolecule Angewandte Chemie via New Scientist Organic chemists in Switzerland have built a ginormous virus-sized macromolecule - it has 170,000 bond-forming chemical reactions - calling it a major step in the creation of molecular objects. The molecule, called PG5, is the biggest synthetic molecule with a stable, defined form. Similar structures exist in nature, but they are hard to duplicate, because they fall apart during creation, as New Scientist explains. Future molecular objects would need to keep their structure regardless of their environment, and PG5 is a step in this direction. Its structure is similar to that of a tobacco virus, and it keeps this rod-like structure in various conditions - it resists flattening out on a surface, for instance. PG5 is 10 nanometers in diameter and weighs as much as 200 million hydrogen atoms. This is far bigger than the previous record-holder, polystyrene polymers that were...

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