Scientists Capture All The Neurons Firing Across A Fish's Brain On Video
It's like brain fireworks. A month ago, a team of Japanese scientists managed to capture a zebrafish's thoughts on video. Now, you can now watch the entire brain of a larval zebrafish light up as its individual neurons fire. This work, featured in Nature Methods this week, provides the most complete imaging of single-neuron brain activity in a vertebrate to date. Using light-sheet microscopy, researchers from the Howard Hughes Medical Institute's Janella Farm Research Campus were able to record flashes of brain activity in a fish every 1.3 seconds, showing 80 percent of its 100,000 neurons. The imaging system developed by study authors Philipp Keller and Misha Ahrens can't distinguish between neurons that fire once and those that fire multiple times in a short period, but it does show how neural activity moves through the brain. It'll hopefully allow researchers to better analyze how regions of the brain work together...