Novel role of protein in generating amyloid-beta peptide
Tuesday, April 28, 2009 - 11:49
in Health & Medicine
A defining hallmark of Alzheimer's disease is the accumulation of the amyloid ? protein (A?), otherwise known as "senile plaques," in the brain's cortex and hippocampus, where memory consolidation occurs. Researchers at the University of California, San Diego School of Medicine have identified a novel protein which, when over-expressed, leads to a dramatic increase in the generation of A?.