What's the influence of laxative agents on mucosal barrier repair?

The prostone lubiprostone has been shown to stimulate chloride secretion via one of the minor intestinal epithelial channels, ClC-2. This results in sustained low-level secretion of water into the lumen. Previous studies by the same research group have identified ClC-2 as a key protein involved in re-assembly of interepithelial tight junctions...

Read the whole article on

More from