Helicobacter pylori can multiply in autophagic vesicles

Helicobacter pylori, a Gram-negative, flagellated, microaerophilic bacterium, can selectively colonise in the human stomach. Its infection is widespread throughout the world, and is present in about 50% of the global human population with 80% in developing countries and 20-50% in industrialised countries. Infection of the stomach with H. pylori induces a local immune response with infiltration of the mucosa by macrophages, neutrophils and lymphocytes. Although the innate and adaptive immune responses are activated, the bacterium is rarely eliminated and infections can last for decades if left untreated...

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