Long-lasting nerve block could change pain management

Researchers at Children's Hospital Boston have developed a slow-release anaesthetic drug-delivery system that could potentially revolutionise treatment of pain during and after surgery, and may also have a large impact on chronic pain management. In NIH-funded work, they used specially designed fat-based particles called liposomes to package saxitoxin, a potent anaesthetic, and produced long-lasting local anaesthesia in rats without apparent toxicity to nerve or muscle cells. The research was published online 13 April by the Proceedings of the National Academy of Sciences...

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