Chemotherapy resistance: Checkpoint protein provides armour against cancer drugs

Friday, August 28, 2009 - 23:47 in Health & Medicine

Cell cycle checkpoints act like molecular tripwires for damaged cells, forcing them to pause and take stock. Leave the tripwire in place for too long, though, and cancer cells will press on regardless, making them resistant to the lethal effects of certain types of chemotherapy, according to researchers at the Salk Institute for Biological Studies...

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