Protective role for copper in Alzheimer's disease
Friday, October 9, 2009 - 05:49
in Health & Medicine
Two articles in a forthcoming issue of the Journal of Alzheimer's Disease by Dr Chris Exley, Reader in Bioinorganic Chemistry in the Research Institute for the Environment, Physical Sciences and Applied Mathematics at Keele University, UK, ('Copper abolishes the beta-sheet secondary structure of preformed amyloid fibrils of Abeta42') and Dr Zhao-Feng Jiang, of Beijing Union University, Beijing, China ('Coordinating to three histidine residues: Cu(II) promoting oligomeric, fibril amyloid beta peptide to aggregate in a non-beta-sheeted way') have confirmed a potentially protective role for copper in Alzheimer's Disease...