Key player found for a cancer typical in Down syndrome
Friday, March 19, 2010 - 09:08
in Health & Medicine
Between 5 and 10 percent of babies with Down syndrome develop a transient form of leukaemia that usually resolves on its own. However, for reasons that haven't been clear, 20 to 30 percent of these babies progress to a more serious leukaemia known as Down syndrome acute megakaryoblastic leukaemia (DS-AMKL), which affects the blood progenitor cells that form red blood cells and platelets. Now, researchers at Children's Hospital Boston have found a gene regulator they believe to be a key player in DS-AMKL, advancing understanding of how the disease develops and how to treat it...
