Protein highways keep tissues organised

Tuesday, October 19, 2010 - 08:40 in Biology & Nature

Precise regulation of tissue architecture is critical for organ function. Single cells build up a tissue by communicating with their environment and with other cells, thereby receiving instructions on whether to divide, change shape or migrate. An interdisciplinary group of researchers from several Max Planck Institutes have now identified a mechanism by which skin cells organise their interior architecture as a response to signals from their surroundings. 'Cells react to changes in their environment very rapidly. To do this, cells need to have their signalling machinery at the right place at the right time' says Sara Wickstroem, a researcher from the Max Planck Institute of Biochemistry...

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