Trace amounts of microbe-killing molecules predict chronic granulomatous disease survival
Tuesday, January 4, 2011 - 16:50
in Health & Medicine
Investigators at the National Institutes of Health have observed that the survival rate of people with a rare immunodeficiency disease called chronic granulomatous disease (CGD) is greatly improved when even very low levels of microbe-killing molecules are present. Because production of these molecules, made by an enzyme called NADPH oxidase, can be predicted from genetic analysis, a patient's risk for severe CGD could be assessed very early in life, allowing for more personalised treatment, say the researchers...