Stem Cell-Like Cancer Cells Resistant To Standard Therapy, Responsive To Targeted Therapy
Wednesday, April 30, 2008 - 13:55
in Health & Medicine
A comparison of breast cancer biopsies before and after treatment show that a subset of cells, which have stem cell-like properties, are resistant to standard chemotherapy. Tumors treated with lapatinib, which inhibits a pathway important for self-renewal, retained a smaller fraction of these tumorigenic cells after therapy.