Pain Free Without Numbness -- Substance Combination With Chili Peppers

Friday, May 16, 2008 - 11:28 in Health & Medicine

A dentist's injection typically causes numbness for several hours. This experience could soon be history. Now, researchers have developed a combination of two agents which is able to specifically block pain without producing numbness or motor paralysis. The substance is composed of a normally inactive derivative of the local anesthetic lidocaine, called QX314, and capsaicin, the pain-producing substance in chili peppers. Capsaicin works by opening channels present only in pain fibers to allow the QX314 only into these cells, where it blocks their function.

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