Scientists Trace A Novel Way Cells Are Disrupted In Cancer

A research team at Cold Spring Harbor Laboratory is clarifying a previously unappreciated way that cellular processes are disrupted in cancer. Following upon previous work showing that a splicing factor called SF2/ASF can induce tumors in cell cultures, the team now shows that the same splicing factor induces changes in proteins in a pathway called PI3K-mTOR well known for its involvement in cancers.

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