New Tumor Inhibitor For Treatment Of Hereditary Breast Cancer Shows Promising Results In Mouse Model
Thursday, October 30, 2008 - 07:21
in Health & Medicine
Researchers used the novel inhibitor AZD2281 to target breast cancer, in which the BRCA1-gene plays a role, in a genetically engineered mouse model. Treatment resulted in tumor regression and a strong increase in survival without signs of toxicity. The inhibitor, which recently entered trials in human cancer patients, thus seems to have therapeutic potential for BRCA-defective tumors.