Tailor-made Recombinant Proteins In Mammals
Saturday, February 14, 2009 - 19:35
in Biology & Nature
"Aldehyde tags" are used to label proteins in bacterial recombinant-DNA systems -- and now in proteins that can only be expressed by mammalian systems. While some recombinant drugs like insulin are made in bacterial systems, most have to be produced by mammalian cells. Aldehyde tags direct chemical modifications to specific sites on proteins, including monoclonal antibodies and other therapeutics important in the pharmaceutical industry.
