Key Decision-point At Which Cells With Broken DNA Repair Themselves Or Die Identified

Cells that undergo potentially catastrophic damage must make a decision: either to fix the damage or program themselves for death, a process called apoptosis. Scientists have found that the protein Eyes Absent regulates intracellular signals at this decision point to allow the formation of specialized microenvironments on DNA, called gamma-H2A.X foci, which let the cell to summon repair enzymes to the site of broken DNA strands.

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