How Deadly Pediatric Disorder Develops In Brain: Link To Alzheimer's Could Lead To First Treatment

A deadly brain disorder in toddlers may find its first treatment in drugs for Alzheimer's disease. Scientists have discovered how a form of the rare genetic disease known as Sanfilippo syndrome develops in the young brain, causing severe mental retardation and death as early as age 14. Published this week in the early online edition of Proceedings of the National Academy of Sciences, the findings suggest that new Alzheimer's drugs may provide therapy for the currently untreatable metabolic disorder.

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