Researchers Reconstitute Enzyme That Synthesizes Cholesterol Drug Lovastatin
Monday, November 9, 2009 - 23:35
in Health & Medicine
Researchers have for the first time, successfully reconstituted one of the most interesting but least understood enzymes in the highly reducing iterative polyketide synthases found in filamentous fungi. This enzyme is responsible for producing the cholesterol-lowering compound lovastatin. Lovastatin is a blockbuster drug used for lowering cholesterol in those with hypercholesterolemia, and thus helps to prevent cardiovascular disease.