Most plentiful cell type in the heart -- the fibroblast -- contributes to heart failure

Monday, December 21, 2009 - 23:21 in Health & Medicine

Fibroblasts are the most numerous cell type in the heart, but they are considered to have a less important role in heart failure than heart muscle cells. However, a team of researchers has now determined that fibroblasts are essential for the response of the mouse heart to conditions that mimic high blood pressure, a response that if sustained ultimately leads to heart failure.

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