Role for immune cells known as mast cells in atrial fibrillation

Tuesday, December 22, 2009 - 20:14 in Health & Medicine

Atrial fibrillation (Afib) is the most common type of abnormal heart beat. It is characterized by scarring of the atrial region of the heart (a hallmark known as atrial fibrosis). Although atrial fibrosis is thought to perpetuate Afib, exactly how it develops has not been determined. Some research has suggested a role for inflammation in the process. Consistent with this, a team of researchers has now identified a role for immune cells known as mast cells in inducing atrial fibrosis and Afib in a mouse model of the condition.

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