How ubiquitin chains are added to cell-cycle proteins: May lead to targeted cancer therapies

Sunday, January 3, 2010 - 21:14 in Biology & Nature

Researchers have been able to view in detail, and for the first time, the previously mysterious process by which long chains of a protein called ubiquitin are added by enzymes called ubiquitin ligases to proteins that control the cell cycle. Ubiquitin chains tag target proteins for destruction by protein-degrading complexes in the cell.

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