Brain tumor's 'grow-or-go' switch discovered

High energy levels cause glioblastoma cells to proliferate; low levels cause them to grow less and to migrate. This study discovered that a molecule called miR-451 coordinates this grow-or-go behavior, which is closely linked to the cells' ability to invade and spread. Thus, the molecule might be a biomarker for predicting survival in patients with glioblastoma multiforme and may serve as a target to develop drugs to fight these tumors.

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