Reducing the toxicity of lithium
Wednesday, June 9, 2010 - 22:20
in Health & Medicine
Lithium is the most effective treatment for bipolar disorder. However, its use is limited because of neurological side effects and a risk for overdose-induced toxicity. Researchers have now delineated a molecular pathway by which chronic administration of therapeutic doses of lithium has negative effects in mice and hope that these data might provide new ideas for combination therapies that diminish the toxicities of lithium.