Genetic link to advanced fatty liver disease confirmed by new studies

Tuesday, August 17, 2010 - 15:14 in Health & Medicine

Researchers have found that patients with nonalcoholic fatty liver disease (NAFLD) who carry an allele of the PNPLA3 gene have an increased risk of developing advanced disease, including nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. Another study validates these findings and further concludes that in pediatric patients, the same allele is associated with earlier disease presentation.

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