Protein clamps tight to telomeres to help prevent aging and support cancer

Sunday, September 19, 2010 - 09:14 in Biology & Nature

Researchers have published the first detailed report on the structure and function of a crucial domain in the protein known as Cdc13, which sustains telomeres by clamping to DNA and recruiting telomere-lengthening enzymes to the area. The study was performed using the yeast gene, however, this essential life process has changed little through evolution, and evidence suggests that the human equivalent of this protein may make a good target for future anticancer drugs.

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