Art of dividing: Researchers decode function and protein content of the centrosome

Tuesday, September 21, 2010 - 22:14 in Biology & Nature

A basic requirement for growth and life of a multicellular organism is the ability of its cells to divide. Chromosomes in the cells duplicate and are then distributed among the daughter cells. This distribution is organized by a protein complex made up of several hundred different proteins, called the centrosome. In cancer cells, the centrosome often assumes an unnatural shape or is present in uncontrolled numbers. The reasons for this were previously largely unknown. Scientists in Germany have now investigated the functions of the different centrosomal components and report their findings.

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