New strain of 'high-runner' rats uniquely resistant to disease

Everybody knows that if you're physically fit, you're less likely to get a wide range of diseases. What most people don't know is that some people are "naturally" in better shape than others, and this variation in conditioning makes it difficult to test for disease risk and drug effectiveness in animal models. A new research paper started out as a study to explain the strong statistical link between low aerobic exercise capacity and common diseases, but ultimately led to an animal model that breaks through the limitations of current systems that target single disease pathways.

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