NSAID receptor responsible for olive oil's 'cough' and more
Thursday, January 27, 2011 - 16:11
in Health & Medicine
Scientists report that two structurally unrelated anti-inflammatory compounds both activate the TRPA1 receptor. One, oleocanthal, is found in extra virgin olive oil while ibuprofen is an over-the-counter non-steroidal anti-inflammatory drug. The researchers also localized the TRPA1 receptor to the back of the throat, which is where the distinctive irritating sting from olive oil is felt. The findings may provide novel insights into anti-inflammatory pharmacology.