Bacteria: Chemists monitor single-molecule switching in action
Monday, May 2, 2011 - 10:30
in Biology & Nature
In various ways, bacteria are one step ahead to us humans. For example, they dispose of "intelligent" RNA molecules, so-called riboswitches, which help to regulate many of their essential metabolism pathways. The riboswitches, only discovered a few years ago, are sensors in RNA molecules. A riboswitch acts similarly to a motion sensor that switches on or off the light when people are nearby: the riboswitch switches genes off or on when certain metabolism products are present in a cell. There is no similar mechanism of gene regulation in humans, therefore this represents an ideal target for new antibiotics.