Loss of protein SPDEF allows prostate cancer cells to gain foothold at possible sites of metastasis

Prostate cancer kills only by metastasis to other tissues. A new study shows likely mechanism required for this metastasis: cells' loss of protein SPDEF. The presence of SPDEF could be used to recognize prostate cancers that can't kill and so don't require treatment. Adding SPDEF back to cancer cells that have lost it may remove cells' ability to metastasize.

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