Resistance to visceral Leishmaniasis: New mechanisms involved
Thursday, May 16, 2013 - 10:30
in Health & Medicine
Researchers have elucidated new molecular mechanisms involved in resistance to visceral leishmaniasis, a serious parasitic infection. They have shown that dectin-1 and mannose receptors participate in the protection against the parasite responsible for this infection, by triggering an inflammatory response, while the DC-SIGN receptor facilitates the penetration of the pathogen and its proliferation in macrophages.