Tiny antisense molecules increase 'good cholesterol' levels in obese primates

Thursday, November 21, 2013 - 16:00 in Health & Medicine

A strategy to increase levels of beneficial high-density lipoprotein (HDL) has been shown for the first time to be effective in non-human primates. The approach uses tiny antisense sequences to block the action of microRNAs that would otherwise inhibit a protein required for generation of HDL, the "good cholesterol" that helps remove harmful lipids from the body.

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