AML score combining genetic, epigenetic changes might help guide therapy
Wednesday, January 8, 2014 - 16:10
in Health & Medicine
Currently, doctors use chromosome markers and gene mutations to determine the best treatment for patients with acute myeloid leukemia. But a new study suggests that a score based on seven mutated genes and the epigenetic changes that the researchers discovered were also present might help guide treatment by identifying novel subsets of patients. Patients with a low score had the best outcomes, and those with high scores had the poorest outcomes.