Is zinc the missing link for osteoarthritis therapies?

Friday, February 14, 2014 - 14:31 in Biology & Nature

A study reveals that osteoarthritis-related tissue damage is caused by a molecular pathway that is involved in regulating and responding to zinc levels inside of cartilage cells. A protein called ZIP8 transports zinc inside these cells, setting off a cascade of molecular events that result in the destruction of cartilage tissue in mice. The findings could lead to a new generation of therapies for osteoarthritis.

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