Scientists find cell fate switch that decides liver, or pancreas?

Friday, February 14, 2014 - 14:30 in Biology & Nature

Stem cell scientists have a new theory for how stem cells decide whether to become liver or pancreatic cells during development. A cell's fate, the researchers found, is determined by the nearby presence of prostaglandin E2, a messenger molecule best known for its role in inflammation and pain. The discovery could potentially make liver and pancreas cells easier to generate both in the lab and for future cell therapies.

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