Molecular 'cocktail' transforms skin cells into beating heart cells
A new method has been devised that allows for the more efficient -- and, importantly, more complete -- reprogramming of skin cells into cells that are virtually indistinguishable from heart muscle cells. These findings, based on animal models, offer new-found optimism in the hunt for a way to regenerate muscle lost in a heart attack. Heart disease is the world's leading cause of death, but recent advances in science and medicine have improved the chances of surviving a heart attack. In the United States alone, nearly 1 million people have survived an attack, but are living with heart failure—a chronic condition in which the heart, having lost muscle during the attack, does not beat at full capacity. So, scientists have begun to look toward cellular reprogramming as a way to regenerate this damaged heart muscle.