New clues found to preventing lung transplant rejection

Wednesday, February 26, 2014 - 13:51 in Health & Medicine

Broadly suppressing the immune system after lung transplantation may inadvertently encourage organ rejection, according to a new study in mice. Organ transplant patients routinely receive drugs that stop their immune systems from attacking newly implanted hearts, livers, kidneys or lungs, which the body sees as foreign. In a surprising discovery, researchers found that newly transplanted lungs in mice were more likely to be rejected if key immune cells were missing, a situation that simulates what happens when patients take immunosuppressive drugs.

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