Combined hormone therapy clinical trial yields massive economic return

The overall economic return from a combined hormone therapy clinical trial indicates that changes in practice stemming from the trial provided a net economic return of $37.1 billion over the 10-year period since the main findings were published. "The motivation for the first WHI trial was to see if we could prevent heart disease, the number one killer of women. That's why we did it -- the economics never occurred to me," said the lead investigator. What these findings underscore is the significant role clinical trials play in science and the importance of continuing to find ways to strategically invest public research funds to maximize value to society."

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