First method for generating specific, inheritable mutations revealed by researchers
Thursday, May 8, 2014 - 18:32
in Biology & Nature
The first method for generating specific and inheritable mutations in the species of the Platynereis model system has been revealed by researchers. The researchers found out that the induced mutations are heritable, demonstrating that TALENs can be used for generating mutant lines in this bristle worm. "This new tool opens the door for detailed in vivo functional analyses in Platynereis and can also facilitate further technical developments. For example, we hope to use TALENs to insert fluorescent reporter genes into the genome. In this way we can study how gene expression is regulated across the entire lifecycle," explains the study's first author.