New microscopy technique yields fresh data on muscular dystrophy

Thursday, September 18, 2014 - 11:01 in Biology & Nature

A new microscopy technique yields resolution an order of magnitude better than previously possible. Through this new technique, the researchers showed that dystrophin was responsible for regulating tiny molecular fluctuations in calcium channels while muscles are in use. The discovery suggests that a lack of functional dystrophin alters the dynamics of ion channels -- helping to cause the defective mechanical responses and the calcium imbalance that impair normal muscle activity in patients with muscular dystrophy.

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